New Discovery Causes Leukemia Cells To Destroy Themselves

We must point out that these cells only attack and destroy other leukemia cells, but they are not effective against those that cause other types of cancer.
New discovery causes leukemia cells to destroy themselves

Leukemia is a type of blood cancer that consists of leukemia cells and starts in the bone marrow, which is tissue found in the middle of certain bones. This is where most of the blood cells are created.

The disease starts when immature blood cells turn into cancer cells. This prevents sufficient amounts of red blood cells, platelets and healthy white blood cells from forming. This then triggers a series of fatal symptoms that increase as the number of good cells decreases.

The cancer spreads through the bloodstream and lymph nodes. As it develops, it can even reach the brain, spine and other parts of the body.

Although scientific advances have developed various treatments to combat this disease, it unfortunately continues to be one of the most difficult to treat. Patients undergoing treatment generally experience constant relapses because the cells often become resistant to the drug.

The research on leukemia cells

blood

Researchers at The Scripps Research Institute (TSRI) in La Jolla, California, have developed a new technique that can cause leukemia cells to transform into immune cells to destroy the cancer, which grows uncontrollably and therefore complicates the disease.

The key to making this possible is a fairly rare type of human antibody. It activates receptors in the marrow cells to induce maturation and convert them into useful cells.

Antibodies are a type of protein that is naturally formed by the human body’s immune system. They work with white blood cells to fight any external invaders. This can be to neutralize them or destroy them.

With this in mind, researchers are trying to develop a treatment that includes antibodies, which can convert leukemia cells in the bone marrow to non-cancer cells.

They hoped that the antibodies would have the ability to activate immature cells to make them healthy and useful again to treat cells that were already damaged.

cancer cells

What happened then?

After years of research, however, they had never expected that a group of these introduced antibodies could help cells to mature into very different varieties, such as dendritic cells which are the key to boosting the body’s immune response.

In order to understand such an important finding, the researchers added several antibodies to a human blood sample that had many dangerous leukemia cells. They discovered that they could transform the dangerous cells into other cell variants, which actually supported the immune system.

After giving the cells even more time to function, they began to mature and slowly began to resemble cells responsible for finding and destroying threats to the body, including viruses, bacteria and leukemia cells.

The NK cells, also known as the “natural killer cell”, were even shown to have the ability to affect cancer cells. They were able to destroy up to 15% of the leukemia cells in the sample in just one day.

Although it sounds incredible, this group of cells killed only the leukemia cells. But not those that cause other types of cancer in the body.

Good expectations…

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With the incredible results of the study, the researchers hope that this treatment can be used to transform a wide range of NK cancer cells so that it can completely cure patients.

Research leader Richard A. Lerner said; “This is a completely new focus for cancer, and we are working to test it on human patients as soon as possible.”

He then added; “We are discussing this with pharmaceutical companies in order to provide it to humans after the necessary preclinical toxicity studies”:

So, to summarize: this is a very beneficial treatment. These antibodies may be useful with few or no further modifications.

It is believed that they significantly reduce the side effects of current treatment programs, and that it is more tolerable for the body than chemotherapy.

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